Description
Product Characteristics:
Alpha 2 Antiplasmin is a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Subcellular location: Secreted
Synonyms: A2AP, A2AP_HUMAN, AAP, Alpha 2 antiplasmin, Alpha 2 antiplasmin pigment epithelium derived factor, Alpha 2 AP, ALPHA 2 PI, Alpha 2 plasmin inhibitor, Alpha 2 plasmin inhibitor deficiency, Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-PI, Alpha-2-plasmin inhibitor, Antiplasmin deficiency, API, Plasmin inhibitor deficiency, PLI, Serine or cysteine peptidase inhibitor, clade F, member 2, Serine Or cysteine peptidase inhibitor, clade F, member 2, isoform CRA_c, Serine or cysteine proteinase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2, Serine Or cysteine proteinase inhibitor, clade F, member 2, Serine or cysteine peptidase inhibitor clade F member 2, Serpin F2, Serpin peptidase inhibitor clade F, Serpin peptidase inhibitor, clade F alpha 2 antiplasmin pigment epithelium derived factor member 2, SERPINF2.
Target Information: This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]